Avast and AVG seem to be blocking the Sims 4 user folder since Patch 1.67.45/ 1.32 which prevents the game from using certain files and folders.
This shows with the following symptoms:
- C:\Programme\Electronic Arts\EA Desktop\EA Desktop\EADesktop.exe (Path can vary depending on where you installed EA app)
- C:\Program Files (x86)\Origin\Origin.exe (Path can vary depending on where you installed Origin)
- <Installation Path>\The Sims 4\Game\Bin\TS4_x64.exe
- <Installation Path>\The Sims 4\Game\Bin_LE\TS4.exe