Origin not running (d3382ced:984c6a38:00000000)

Problem

When I try to start the game, I get the following error message:

Unable to Start: Origin is not running, make sure that it is running before attempting to play the Sims 4 [d3382ced:984c6a38:00000000]

OriginNotRunning

Cause

The Sims 4 needs the latest version of Origin installed. This message is very common if you upgraded to Windows 10 (or if you run an illegal version in which case you’re out of luck)

Solution

You won’t loose your games by uninstalling Origin but you temporarily can’t play them. Make sure to login with the same account after reinstalling.
Where can I find my installation folder ?
The following tips need to be done for the exe-File of the game. It's best to do it for both the 32 bit Version (TS4.exe) as well as TS4_64.exe). Also add the Origin.exe file. Both Sims files can be found in the folder <Installation folder>\Game\Bin and \Game\Bin_LE The Origin file can be found in the folder you installed Origin in (Default: c:\programs(x86)\Origin)

More suggestions

Other things to try

Further Reading